Liver Metastasis: An Unsung Etiology of Hepatorenal Syndrome

Pulak Azad¹, Yasir Rizvi², Lakshmi Kant Jha², Vansh Arora¹, and Raajit Chanana³

¹DrNB Resident, Dharamshilla Narayana Superspeciality, India
²Senior Consultant and Director, Nephrology, Dharmashilla Narayana Superspeciality Hospital, India
³Senior Consultant, Medical Oncology, Dharmashilla Narayana Superspeciality Hospital, India

*Corresponding Author: Pulak Azad, DrNB resident, Nephrology, Dharamshilla Narayana Superspeciality, Delhi, India.

DOI: 10.64258/3067-7130.2025.1020014

Submission Date: April 19, 2025

Published Date: April 29, 2025

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Abstract

Hepatorenal syndrome is a reversible acute kidney injury affecting patients with acute liver failure, cirrhosis or acute on chronic liver failure. The tsunami of metastatic liver disease and their various presentations has always intrigued the clinicians. Liver metastasis attributing to hepatorenal syndrome in otherwise normal liver parenchyma is a less considered and often an ignored etiology. Secondly less aggressive treatment approach of such patients has also shielded its presence. We present a case of pancreatic malignancy with liver metastasis who had Icterus, ascites, coagulopathy and altered sensorium. In due course of stay in the hospital patient\'s urine output reduced and serum creatinine got elevated. Diagnosis of hepatorenal syndrome was made and treatment was initiated. Outcome of such patients on a large scale could provide a better picture for their prognosis and at the same time empower efforts of clinicians.

Keywords

Hepatorenal syndrome, Liver metastasis, Acute kidney injury, Metastatic cancer, Parenchymal liver diseases

Citation

Pulak A, Yasir R, Lakshmi KH, Vansh A, Raajit C (2025) Liver Metastasis: An Unsung Etiology of Hepatorenal Syndrome. On J Clin & Med Case Rep 1(3): 1-4