Biomarkers In the Diagnosis and Assessment of Treatment Effectiveness in a Child with Autism

Dakukina TV¹, Abydova NB², Gaidukevich IV¹, Mityukova TA³, Polulyakh OE³, and Tukalo MI⁴*

¹Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Belarus
²Medical Center Davr, Uzbekistan
³Institute of Physiology, National Academy of Sciences of Belarus, Belarus
⁴Republic Scientific and Practical Center for Mental Health, Belarus

*Corresponding Author: Dakukina TV, Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus.

DOI: 10.64258/3067-7130.2025.1020023

Submission Date: July 7, 2025

Published Date: July 11, 2025

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Abstract

It is known that children with autism do not respond well to psychological and speech therapy correction and pharmacological treatment. A pressing question of our time is the personalized selection of alternative treatment methods based on data from modern diagnostic methods. The article presents a typical case of autism taking into account history, psychological characteristics, pharmacogenetic testing, EEG features, and results of laboratory studies of serum (BDNF, progranulin, antibodies to myelin basic protein, glutamate). The effectiveness of the therapy being conducted is assessed using biomarkers.

Keywords

Autism, Biomarkers, Neurotrophic Proteins, Antibodies to Myelin Basic Protein, Glutamate, Computer EEG, Motor Response Threshold.

Citation

Dakukina TV, Abydova NB, Gaidukevich IV, Mityukova TA, Polulyakh OE et al. (2025) Biomarkers in the Diagnosis and Assessment of Treatment Effectiveness in a Child with Autism. On J Clin & Med Case Rep 1(5): 1-11.